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High-Quality Brain Perfusion SPECT Images may be achieved with ​ a High-Speed Recording Using 360° CZT Camera​

Article Link Open Access: https://rdcu.be/b9Ynn

Manon Bordonne, Mohammad B. Chawki, Pierre-Yves Marie, TimothéeZaragori, VéroniqueRoch, Rachel Grignon, Laetitia Imbert & Antoine Verger CHRU Nancy

The present study results, based on concordant data from phantom and patients, as well as from quantitative and qualitative visual analyses, show that the quality of brain perfusion SPECT images can be significantly enhanced by acquisition using a dedicated brain configuration for recordings obtained from a 360° CZT camera, as compared with an Anger camera. Furthermore, this enhancement may be achieved with a high-speed recording of no more than 15 min, a property that is particularly useful in patients with neurological diseases and for whom a brain perfusion SPECT may be indicated.

Pertinent Findings: compared with the Anger camera, the CZT camera provides greater than 2-fold increase in count sensitivity and higher image quality performance (up to 119% of enhancement in spatial resolution and 41% in gray/white matter contrast). These image quality enhancements are observed both quantitatively and visually, with all performance parameter results remaining unchanged even when CZT images are obtained with reduced 15 min recording time.

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